Projects

E-cigarette and Sexual Function

This project brings together my doctoral research on the toxicological effects of e-cigarette exposure, with emphasis on reproductive health, sexual function, Leydig cell steroidogenesis, testosterone signaling, mitochondrial dysfunction, and secondhand aerosol exposure.

Some of these works were supported by the Ministry of Higher Education Malaysia through the Fundamental Research Grant Scheme (FRGS/1/2020/SKK05/UM/02/1) and the UMSC C.A.R.E Fund (UMG010C-2022). Refer to the Acknowledgement section on the publication page.

• Ferroptosis in e-cigarette aerosol-associated respiratory injury (DOI: 10.1007/s00204-026-04486-w)
• Could e-cigarette devices generate inhalable micro- and nanoplastics? Exposure plausibility and reproductive relevance (DOI: 10.1080/15376516.2026.2695155)
• E-cigarettes and erectile dysfunction (DOI: 10.1038/s41443-026-01300-0)
• Leydig cell steroidogenic pathways (DOI: 10.1016/j.mce.2026.112786)
• MicroRNA-mediated testosterone signaling (DOI: 10.1016/j.etap.2026.104994)
• Mitochondrial dysfunction (DOI: 10.1016/j.tox.2025.154339)
• Secondhand aerosol exposure and lung health (DOI: 10.1007/s10389-026-02740-0)
• E-cigarettes as metabolic disruptors (DOI: 10.1080/15376516.2026.2658739)

Cellular Signaling as Dynamic Regulatory Circuits

This personal project develops a conceptual framework for interpreting cellular signaling pathways as dynamic regulatory circuits rather than static molecular switches. Its sole objective is to advance scientific understanding, and therefore it does not receive any funding.

• NRF2-KEAP1 as a redox signal-resolution circuit (DOI: 10.1016/j.pbiomolbio.2026.03.005)
• CYP1A1 as an environmental sensing feedback circuit (DOI: 10.1007/s00204-026-04384-1)
• More coming soon!

Miscellaneous Sole-Author Works

This section collects articles that do not belong directly to the PhD thesis project or the cellular signaling framework.

• Adipose-driven erectile dysfunction (DOI: 10.1111/dom.70818)