Curriculum Vitae
CV of Ardie Barry Sailis, toxicology researcher in Petaling Jaya, Selangor, with publications, experience and training
Ardie Barry Sailis
Researcher · Toxicology and molecular biology
Petaling Jaya, Selangor, Malaysia
Profile
Toxicology researcher studying how e-cigarette use affects male reproductive health. My doctoral work compares cigarette smokers, e-cigarette users and dual users in Malaysia, linking exposure to testosterone-related microRNAs, mitochondrial function and blood cell changes. I have published 15 peer-reviewed papers as sole or first author and review manuscripts for seven international journals. Open to roles in research, medical affairs, regulatory science and science communication.
Education
Malaysia
Thesis on testosterone-related microRNAs, blood cell abnormalities and sexual desire in Malaysian cigarette smokers, e-cigarette users and dual users.
Malaysia
Experience
Doctoral research, Malaysia
- Conducted a comparative study of cigarette smokers, e-cigarette users and dual users in Malaysia.
- Analyzed testosterone-related microRNAs by qPCR alongside hormone and blood cell profiles.
- Used transmission electron microscopy to assess mitochondrial damage in e-cigarette users and controls.
- Wrote mechanistic and systematic reviews on e-cigarette toxicology, reproductive health and redox signaling.
- Developed an independent project, Cellular Signalling as Dynamic Regulatory Circuits, producing conceptual models of signal resolution in NRF2–KEAP1 redox signaling and YAP/TAZ mechanotransduction.
Seven international journals
Reviews manuscripts in toxicology, pharmacology, reproductive health and public health for American Journal of Preventive Medicine, Journal of Hazardous Materials Advances, Pharmacological Reviews, Progress in Biophysics and Molecular Biology, Toxicology Reports, PLOS One and International Journal of General Medicine.
Indah Water Konsortium Sdn Bhd
Supported laboratory operations during a full-time internship, covering microbiology procedures, water quality testing, sample handling, documentation and technical reporting under standard operating procedures.
Publications
- The unfolded protein response as a proteotoxic stress-resolution circuit: branch-selective signaling and failed resolution in environmental immunotoxicity. Chemico-Biological Interactions, 2026. doi.org/10.1016/j.cbi.2026.112392
- YAP/TAZ as a mechanochemical signal-resolution circuit. Progress in Biophysics and Molecular Biology, 2026. doi.org/10.1016/j.pbiomolbio.2026.101960
- Transcriptional condensates as kinetic filters for temporal control of gene expression. Gene Reports, 2026. doi.org/10.1016/j.genrep.2026.102599
- Mitochondrial mechanisms in the potential male reproductive toxicity of e-cigarette-derived metal-containing nanoparticles. Journal of Applied Toxicology, 2026. doi.org/10.1002/jat.70382
- Ferroptosis in e-cigarette aerosol-associated respiratory injury. Archives of Toxicology, 2026. doi.org/10.1007/s00204-026-04486-w
- Could e-cigarette devices generate inhalable micro- and nanoplastics? Exposure plausibility and reproductive relevance. Toxicology Mechanisms and Methods, 2026. doi.org/10.1080/15376516.2026.2695155
- Adipose as a Driver, Not a Bystander: A Modern Synthesis of Obesity-Related Erectile Dysfunction. Diabetes, Obesity and Metabolism, 2026. doi.org/10.1111/dom.70818
- E-cigarette aerosol constituents modulate Leydig cell steroidogenic pathways: Evidence from experimental models. Molecular and Cellular Endocrinology, 2026. doi.org/10.1016/j.mce.2026.112786
- MicroRNA-mediated disruption of testosterone signaling associated with e-cigarette exposure. Environmental Toxicology and Pharmacology, 2026. doi.org/10.1016/j.etap.2026.104994
- NRF2-KEAP1 as a redox signal-resolution circuit: Beyond the antioxidant switch. Progress in Biophysics and Molecular Biology, 2026. doi.org/10.1016/j.pbiomolbio.2026.03.005
- E-cigarettes and erectile dysfunction: biological mechanisms and research challenges. International Journal of Impotence Research, 2026. doi.org/10.1038/s41443-026-01300-0
- E-cigarette aerosols as systemic metabolic disruptors: integrated mitochondrial, circadian, and neurobehavioral mechanisms. Toxicology Mechanisms and Methods, 2026. doi.org/10.1080/15376516.2026.2658739
- CYP1A1 as a conserved metabolic circuit linking environmental sensing to immune regulation. Archives of Toxicology, 2026. doi.org/10.1007/s00204-026-04384-1
- Effects of secondhand exposure to e-cigarette aerosol on lung health: a systematic review. Journal of Public Health, 2026. doi.org/10.1007/s10389-026-02740-0
- Mitochondrial dysfunction induced by E-cigarettes. Toxicology, 2025. doi.org/10.1016/j.tox.2025.154339
Talks and conferences
Poster presentation, ISAM Regional Meeting
UiTM Puncak Alam
Training
- Systematic Literature Review and Meta-Analysis Workshop2025
- UV-Visible Double Beam Spectrophotometer Workshop, Shimadzu2025
- Quantitative PCR (qPCR) Workshop, Vazyme2024
- ic-PHIR Metabolic Workshop, UiTM Puncak Alam2023
Skills
- Laboratory
- qPCR, transmission electron microscopy, molecular biology techniques
- Data
- SPSS, bioinformatics, data interpretation
- Evidence
- Systematic reviews, literature synthesis, mechanistic toxicology
- Writing
- Scientific writing, manuscript preparation, peer review, research conceptualization
- Research areas
- E-cigarette and tobacco toxicology, reproductive health, pharmacology, toxicogenomics, molecular systems biology, mechanotransduction and YAP/TAZ signaling
Languages
- Malay
- Native or bilingual proficiency
- English
- Professional working proficiency
References
Available on request.